@article{de Melo Rodrigues_Lenzi_Lee-Jones_Vieira Wanderley_Marinho Da Silva_Rocha De Carvalho_Teixeira Costa_Galvão De Castro Junior_De Martino Lee_Mendes Lins_Rezende Godinho_Correa Ribeiro_2020, title={Leucemia mielóide aguda em crianças e adolescentes em instituições Brasileiras: realidade e desafios}, volume={1}, url={https://www.jbmtct.com.br/seer/index.php/jbmtct/article/view/34}, DOI={10.46765/2675-374X.2020v2n1p77-86}, abstractNote={<p>Objective: To describe the outcome of acute myeloid leukemia (AML) among children treated in Brazilian institutions. Methods: A structured online questionnaire was sent to pediatric oncologists affiliated to the Brazilian Society of Pediatric Oncology. The physicians and institutions were unidentified. Results: One hundred and four pediatric oncologists in all Brazilian regions answered the questionnaire. The treatment-related mortality rate was reported to be higher than 30% by 29.8% of the participants. Difficulty in accessing the intensive care unit (ICU) was reported by 54.8%. About 85% had access to cytogenetics, 78% to molecular testing, 94% to the measurement of residual disease by flow cytometry. About 90% of participants reported access to HSCT, but 86% of them had difficulties in providing HSCT timely. About 95% of the respondents indicated the need to create a national treatment protocol, and 89.4% are willing to collaborate with a national study group. Conclusion: Our study demonstrated large gaps in the treatment of pediatric AML in Brazil. To improve outcome, a national protocol will have to consider the regional differences and adapt the management according to the local resources.</p>}, number={3}, journal={JOURNAL OF BONE MARROW TRANSPLANTATION AND CELLULAR THERAPY}, author={de Melo Rodrigues, Ana Luiza and Lenzi, Luana and Lee-Jones, Lisa and Vieira Wanderley, Alayde and Marinho Da Silva, Ana Maria and Rocha De Carvalho, Cinthya and Teixeira Costa, Juliana and Galvão De Castro Junior, Cláudio and De Martino Lee, Maria Lucia and Mendes Lins, Mecneide and Rezende Godinho, Patrick and Correa Ribeiro, Raul}, year={2020}, month={Oct.}, pages={77–86} }