CAR-T cell production


  • Martín Bonamino Brazilian National Cancer Institute (INCA)
  • Raquel Melo Alves Paiva Hospital Israelita Albert Einstein
  • Juliana Preto de Godoy Hospital Israelita Albert Einstein
  • Andrea Tiemi Kondo Hospital Israelita Albert Einstein
  • Oswaldo Keith Okamoto Universidade de São Paulo
  • Lucila Nassif Kerbauy Hospital Israelita Albert Einstein



CAR-T cells, GMP manufacturing, viral vector, genetic modification


Cell therapy with T cells expressing chimeric antigen receptor (CAR-T) is a type of immunotherapy that involves the manipulation and reprogramming of immune cells (T lymphocytes) in order to recognize and kill tumor cells. For use in patients, CAR-T cells must be manufcatured inside a GMP facility according to a established procedure. 




How to Cite

Bonamino, M. ., Melo Alves Paiva, R., Preto de Godoy, J., Tiemi Kondo, A., Keith Okamoto, O., & Nassif Kerbauy, L. (2022). CAR-T cell production. JOURNAL OF BONE MARROW TRANSPLANTATION AND CELLULAR THERAPY, 3(1), 155.

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